Società Italiana per lo Studio dell'Emostasi e della Trombosi

        

Scope and methodology
The pathogenesis of cancer-associated disseminated intravascular
coagulation (DIC) is complex and multifactorial. It
could present as a spectrum ranging from clinically asymptomatic,
but with laboratory markers of coagulation activation,
to the extreme cases of therapy-resistant thrombosis or
bleeding [1]. In this guidance, we try to address some practical
considerations for this clinical scenario. This statement
will provide clinicians with guidance on how best to manage
DIC in patients with cancer and offer expert consensus to
help decision-making in challenging situations.
The guidance statements in this document are similar to
previous ones [2]. The wording ‘we recommend’ indicates a
strong consensus among the panel members, whereby the
clinician should consider adopting the practice in most
cases. The wording ‘we suggest’ reflects a weak guidance
statement with moderate consensus among the panel members,
whereby the clinician may adopt the guidance statement
or use an alternative approach to manage patients...

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